Afuresertib (GSK2110183) DistillingAfuresertib (GSK2110183) is a potent, orally bioavailable Akt inhibitor with Ki of 0. 08 nM, 2 nM, and 2. 6 nM for Akt1, Akt2, and Akt3, respectively. Phase 2.
AZD1480 is a novel ATP-competitive JAK2 inhibitor with IC50 of 0
2-Tribromoethanol is an organic compound used to anesthetize mice
suppresses the production of proinflammatory proteins by macrophages and blocks acute inflammation
BMS-833923 is an orally bioavailable Smoothened antagonist
Zebularine is a DNA methylation inhibitor that forms a covalent complex with DNA methyltransferases
Time and statistic data diagrams on series of weighments
Dipyridamole (Persantine) is a phosphodiesterase inhibitor that blocks uptake and metabolism of adenosine by erythrocytes and vascular endothelial cells
Ibuprofen (Dolgesic) is an anti-inflammatory inhibitor targeting COX-1 and COX-2 with IC50 of 13
6-fold selective over MCT2
-D-mannopyranoside can be used as an intermediate for chemical sythesis and is a competitor inhibitor of the binding of mannose by Escherichia coli
inhibition of T-cell proliferation and anti-rheumatoid activity
It inhibits lipoxygenases (LOs)
